Osteoporosis is a systemic skeletal disorder characterized by low bone mass and a consequent increase in fracture risk. It is the most common reason for a broken bone among the elderly.

Osteoarthritis (OA) is a type of degenerative joint disease that results from the breakdown of joint cartilage and underlying bone, which affects 1 in 7 adults in the United States.

Osteopenia, known as "low bone mass" or "low bone density," is a condition in which bone mineral density is low.